منابع مشابه
Stem-Cell-Based Gene Therapy for HIV Infection
Despite the enormous success of combined anti-retroviral therapy, HIV infection is still a lifelong disease and continues to spread rapidly worldwide. There is a pressing need to develop a treatment that will cure HIV infection. Recent progress in stem cell manipulation and advancements in humanized mouse models have allowed rapid developments of gene therapy for HIV treatment. In this review, ...
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Introduction: Despite considerable efforts to control AIDS pandemic, it is still one of the significant infectious concerns worldwide. The advance in medical research has led to the development of highly active antiretroviral therapy with a considerable effect to suppress the disease. However, an effective vaccine capable of eradication the HIV pandemic is not available yet. Failure to develop ...
متن کاملGene therapy for HIV.
Introduction With the advent of highly active antiretroviral therapy (HAART), the therapeutic landscape for HIV infected individuals has changed irrevocably. From what can be likened to a defensive approach to AIDS, juggling prophylactic therapies and treating opportunistic pathogens, HAART has taken us onto the oVensive, restoring a sense of optimism to physicians and patients alike in the dev...
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Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis in cancer cells. However, TRAIL is not toxic against most normal cells. We have accordingly examined by in vivo electroporation whether TRAIL induces apoptosis in renal cell carcinoma. In addition, combination treatment with TRAIL and 5-fluorouracil (5-FU) against renal cell carcinoma was also investigated. The NC...
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ژورنال
عنوان ژورنال: Gene Therapy
سال: 2015
ISSN: 0969-7128,1476-5462
DOI: 10.1038/gt.2015.58